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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYROXD1
All Species:
10
Human Site:
S69
Identified Species:
18.33
UniProt:
Q8WU10
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WU10
NP_079130.2
500
55793
S69
E
F
D
V
E
E
Q
S
S
T
M
L
G
K
R
Chimpanzee
Pan troglodytes
XP_520786
500
55723
S69
E
F
D
V
E
E
Q
S
S
T
M
L
G
K
R
Rhesus Macaque
Macaca mulatta
XP_001098386
500
55757
S69
E
F
D
V
E
E
Q
S
S
T
M
L
E
K
R
Dog
Lupus familis
XP_534871
564
62639
P132
E
F
D
V
E
E
Q
P
K
T
M
L
E
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3TMV7
498
55573
T68
D
V
E
E
Q
P
G
T
M
L
E
S
R
F
P
Rat
Rattus norvegicus
Q68FS6
498
55471
M69
V
E
E
Q
P
S
T
M
L
E
N
R
F
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507787
271
29578
Chicken
Gallus gallus
XP_416422
500
55202
P68
E
F
D
V
E
E
Q
P
S
S
L
L
E
Q
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PBT5
490
54238
P70
E
F
D
I
E
E
Q
P
S
R
V
L
E
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610023
472
52333
E61
L
H
K
F
D
V
R
E
Q
D
V
S
E
M
G
Honey Bee
Apis mellifera
XP_624926
477
53873
D66
Q
F
D
I
E
E
K
D
S
T
V
L
M
K
V
Nematode Worm
Caenorhab. elegans
NP_495754
451
50706
K40
I
S
A
S
S
F
V
K
S
V
E
N
Y
Q
K
Sea Urchin
Strong. purpuratus
XP_782117
495
54197
W68
V
E
E
K
P
S
Q
W
L
E
V
K
C
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.1
74.6
N.A.
85
85.1
N.A.
40.2
77
N.A.
64
N.A.
46.4
50
32.7
57.4
Protein Similarity:
100
99.5
98
81.2
N.A.
90.8
91.5
N.A.
44.4
86.8
N.A.
80.4
N.A.
62.2
66
54
72.2
P-Site Identity:
100
100
93.3
73.3
N.A.
0
0
N.A.
0
66.6
N.A.
53.3
N.A.
0
53.3
6.6
6.6
P-Site Similarity:
100
100
93.3
73.3
N.A.
26.6
6.6
N.A.
0
86.6
N.A.
80
N.A.
20
80
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
8
0
54
0
8
0
0
8
0
8
0
0
0
0
0
% D
% Glu:
47
16
24
8
54
54
0
8
0
16
16
0
39
8
0
% E
% Phe:
0
54
0
8
0
8
0
0
0
0
0
0
8
8
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
16
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
0
0
8
8
8
0
0
8
0
31
16
% K
% Leu:
8
0
0
0
0
0
0
0
16
8
8
54
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
8
0
31
0
8
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
8
0
8
16
% N
% Pro:
0
0
0
0
16
8
0
24
0
0
0
0
0
16
8
% P
% Gln:
8
0
0
8
8
0
54
0
8
0
0
0
0
16
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
8
0
8
8
0
39
% R
% Ser:
0
8
0
8
8
16
0
24
54
8
0
16
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
8
0
39
0
0
0
0
0
% T
% Val:
16
8
0
39
0
8
8
0
0
8
31
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _